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Chol-X™ Cardio Support Formula with Phytosterols and Policosanol

Chol-X™ (CholX) High Potency Cardio Support Formula is a unique combination of natural ingredients that help support cardiovascular health. Chol-X™ contains plant phytosterols, policosanol, green tea extract, garlic, and a combination of vitamins important to heart and vascular health. Chol-X Phytosterols Policosanol

Why Chol-X™ contains Phytosterols (Plant Sterols)

Phytosterols, also known as free plant sterols, are structural components in the cell membranes of plants. Plant sterols naturally occur in relatively low levels in many plant oils, fruits, vegetables and nuts. Clinical studies have shown that a diet high in phytosterols and low in fat can lower the risk of heart disease.†
 
Phytosterols lower heart disease risk by reducing serum LDL cholesterol levels. Clinical studies have found that phytosterols can reduce serum LDL (low-density lipoprotein) or "bad" cholesterol levels and total cholesterol levels but do not affect HDL (high-density lipoprotein) or "good" cholesterol levels. These studies have found that phytosterols may significanly reduce total cholesterol and LDL cholesterol when consumed daily for at least one month.
 
The way that phytosterols lower cholesterol is by competing for the limited space in the intestinal micelles. This significantly decreases cholesterol absorption, which in turn affects synthesis of cholesterol in the liver, reducing the production of LDL Cholesterol.1 Clinical studies have measured a 15% drop in total cholesterol and about a 10% reduction in LDL cholesterol in as little as one month, which is on par with many of the statin drugs.2,3,4,5,6
 
†Twice daily consumption of 400mg of phytosterols as part of a diet low in saturated fat and cholesterol, may reduce the risk of heart disease.    Chol-X™ supplies 450mg of phytosterols per capsule (per serving).

Why Chol-X™ contains Policosanol

Policosanols are a group of solid alcohols derived from sugar cane was. Policosanol has been demonstrated to be remarkably safe and effective at reducing cholesterol levels, and at reducing platelet aggregation.
 
In numerous double-blind studies comparing policosanol to synthetic drugs, and in many double-blind placebo-controlled trials (the gold-standard of tests among the established medical community), Policosanol shines. In the researcher's own words, here's what the studies have to say about Policosanol (please click on the "references" link below, for an extended bibliography):
  • Compared to pravastatin:

    "Two patients on pravastatin discontinued the study because of adverse experiences (myocardial infarction and jaundice, respectively). In conclusion, the effects of policosanol (10 mg/day) on lipid profile, platelet aggregation and endothelemia in older patients with type II hypercholesterolemia and high coronary risk are more favorable than those induced by the same doses of pravastatin."7
  • Compared to lovastatin:

    "Policosanol, but not lovastatin, significantly increased (p < 0.01) [over 99% statistical confidence] levels of HDL-cholesterol (7.5%). Comparison between groups showed that changes in HDL-cholesterol induced by policosanol were significantly greater (p < 0.01) than those induced by lovastatin. Both treatments were safe and well tolerated.
     
    "Adverse reactions were more frequent in the lovastatin group (p < 0.01) than in the policosanol group. In conclusion, policosanol administered at 10 mg/day produces more advantageous changes in HDL-cholesterol and has a better safety and tolerability profile than lovastatin 20 mg/day."8
  • Compared to acipimox:

    "These results indicate that policosanol (10 mg/day) was more effective and well tolerated than was acipimox (750 mg/day) [at reducing total cholesterol] in this study population."9
  • Ability to reduce cholesterol:

    "These findings show the effectiveness of low dose of policosanol lowering total cholesterol and LDL levels and suggest a CHD [coronary heart disease] improvement in middle-aged patients with primary or marginal hyperlipidemia."10
  • Ability to reduce platelet aggregation:

    "The present results demonstrate that policosanol (20 mg day-1) is as effective as ASA [(aspirin), in reducing platelet aggregation] (100 mg day-1). Moreover, combination therapy shows some advantages compared with the respective monotherapies."11

Why Chol-X™ contains Green Tea Extract

Green tea has received much attention over the past two decades from studies that have found that green tea reduces the risk of several specific cancers and linked green tea consumption with longer life expectancy. It is largely believed that green tea's benefits are due to the high levels of anti-oxidant compounds called polyphenols. A lesser-known benefit of these polyphenol compounds is that they prevent the oxidation of LDL cholesterol. When LDL cholesterol is oxidized it forms atherosclerotic plaques, which can ultimately lead to atherscerosis and heart disease (cardiovascular disease). Recent research has found that green tea may benefit the heart not only by preventing the oxidation of LDL cholesterol, but by improving endothelial function and vascular dilatation, thereby increasing blood flow and reducing blood pressure.12

Why Chol-X™ contains Garlic

Garlic has been show to reduce the oxidation of LDL cholesterol and to produce small reductions in blood pressure.13 The most important of the chemical compounds found in garlic preparations are the sulfurs. These include alliin, allicin, thiosulfinates and gamma glutamylcysteine peptides. The antihypertensive, anti-atherosclerotic, and platelet aggregation inhibiting mechanisms of these compounds have not been completely elucidated. However, new research confirms the compound allicin's mechanism of action. Allicin rapidly breaks down to form organic polysulphides (diallyl sulfide, diallyl disulfide, diallyl trisulfide, and ajoene); when these polysulfides come in contact with red blood cells, the red blood cells begin emitting hydrogen sulphide. The hydrogen sulphide triggers the blood vessels to relax, increasing blood flow to the heart and other tissues.13

Why Chol-X™ contains Vitamin C

Most people realize that vitamin C is essential to life and they know that extreme deficiency can lead to scurvy. What they do not realize is that vitamin C is, specifically, essential to vascular health. Without vitamin C, the body can not properly produce collagen, one of the structural elements of blood vessels. Without adequate amounts of vitamin C, the body cannot maintain or repair blood vessels. Additionally, vitamin C performs one more important task in blood vessels: it prevents the oxidation of LDL cholesterol. As explained above, when LDL cholesterol is oxidized it forms plaques in the arteries, which can ultimately lead to hardening of the arteries and vessel blockage. Vitamin C appears to be one the best antioxidants when it come to preventing the oxidation of LDL cholesterol.14

Why Chol-X™ contains Folic Acid, Vitamins B6 and B12

While the B vitamins are essential to your overall health, folic acid, vitamin B6 and vitamin B12 play a special roll in cardiovascular health. Among the various functions that they perform, none maybe as important as their role in reducing homocysteine. Homocysteine is an amino acid that is used to build and maintain tissue in the body. However, the excess build-up of homocycsteine is strongly correlated with cardiovascular disease; perhaps as strong a relationship as smoking or high cholesterol. The B-vitamins are "methyl-group donors". If adequate levels of folic acid, vitamin B6 and vitamin B12 are present in the body, damaging homocysteine is "re-methylated" into the beneficial methionine (an essential amino acid) or the antioxidant glutathione. By supplementing these b-vitamins, the body may be able to convert a build up of a potentially hazardous substance into to potentially beneficial substances.15

Chol-X ™ Supplementation

Chol-X™ Cardio Support Formula suggested use: As a dietary supplement take one capsule, twice daily, or as directed by a healthcare practitioner.
 
†Twice daily consumption of 400mg of phytosterols as part of a diet low in saturated fat and cholesterol, may reduce the risk of heart disease.    Chol-X™ supplies 450mg of phytosterols per capsule (one serving).
 
Chol-X™ Supplement Facts
Serving Size: 1 capsules
Servings per container: 60

Amount Per Serving % Daily Value
Vitamin C (from calcium ascorbate) 52 mg 52%
Vitamin B6 (from Pyridoxine HCL) 1 mcg 50%
Folic Acid 220 mcg 55%
Vitamin B12 (Cyanocobalamin) 4 mcg 67%
Phytosterols (Plant Sterols) 450 mg
Green Tea Extract (50% Polyphenols) 50 mg
Deordorized Garlic Powder 10 mg
Policosanol (from sugar cane) 5 mg
†Daily value not established.

   Other ingredients: Cellulose (plant fiber), magnesium stearate (vegetable source), silicon dioxide.

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